The association between low levels of 25-hydroxyvitamin D and non-specific musculoskeletal pain, including fibromyalgia syndrome, is controversial. Several studies have reported a “positive association” and two others found “no association.”
Serum 25 OH vitamin D levels in patients with fibromyalgia.
Serum 25OHD was measured using different cutoff levels and compared between the groups (< 30 ng/ml, < 20 ng/ml and <15 ng/ml). No statistically significant differences were found between the groups regardless of the cutoff level used. A logistic regression model for predicting women with 25OHD levels 20 ng/ml showed that all the variables examined in both groups (age, country of birth, education) were not statistically significant. They found the expected seasonal variations of 25OHD levels, though these were not statistically significant.And found no association between fibromyalgia and low 25OHD levels as previously suggested in other studies.