sittingEach added hour spent sitting was associated with a 14% increase in coronary artery calcium (CAC) score, independent of traditional risk factors, including physical activity, in a study of middle-aged subjects without cardiovascular disease. (from Heart wire).

The association between vascular calcification and vascular disease has been known to anatomists and pathologists for several hundred years.

In 2010 American College of Cardiology/AmericanHeart Association (ACC/AHA) guidelines on screening for coronary artery disease indicated that measurement of CAC is reasonable (level of evidence B) for cardiovascular risk assessment in asymptomatic adults at Framingham intermediate risk (10 to 20 percent 10-year risk).

Cardiovascular disease (CVD) is common in the general population, affecting the majority of adults past the age of 60 years. As a diagnostic category, CVD includes four major areas:

Coronary heart disease (CHD), manifested by myocardial infarction (MI), angina pectoris, heart failure, and coronary death

Cerebrovascular disease, manifested by stroke and transient ischemic attack

Peripheral artery disease, manifested by intermittent claudication

Aortic atherosclerosis and thoracic or abdominal aortic aneurysm

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