It usually starts with the Stomach- All about disorders of the Metabolism

metabolismRevisiting old text books from medicine refreshes my memories about Metabolism. It is essentially  the process by which our bodies make energy from the food we eat. All foods top state Junk, Organic and quickies have constituents that we read and thrive to control. These are proteins, carbohydrates, and fats. Stomach Enzymes , Chemicals in our digestive system break the food parts down into its smaller parts such as sugar and acids. These are actually the engine runners or the fuel. This energy is stored in tissues, such as your liver, muscles, and body fat.

When the process of metabolism goes faulty, we may have symptoms that take us closer to our prognosis. Best description i could find on the Merck manual is what i would like yo repeat in here,  “Carbohydrates are sugars. Some sugars are simple, and others are more complex. Sucrose (table sugar) is made of two simpler sugars called glucose and fructose. Lactose (milk sugar) is made of glucose and galactose. Both sucrose and lactose must be broken down into their component sugars by enzymes before the body can absorb and use them.”

Metabolic disorder, based on the principle of energy utilization and storage, could be diagnosed by a co-occurrence of three out of five of the following medical conditions: abdominal (central) obesity, elevated blood pressure, elevated fasting plasma glucose, high serum triglycerides, and low high-density lipoprotein (HDL) levels. Metabolic syndrome increases the risk of developing cardiovascular disease and diabetes.

some self parameters to watch are amongst the below listed:

  1. Abdominal obesity: a waist circumference of 102 cm (40 in) or more in men and 88 cm (35 inches) or more in women. For Asian Americans, the cutoff values are ≥90 cm (35 in) in men or ≥80 cm (32 in) in women
  2. Serum triglycerides 150 mg/dl or above.
  3. HDL cholesterol 40mg/dl or lower in men and 50mg/dl or lower in women.
  4. Blood pressure of 130/85 or more.
  5. Fasting blood glucose of 100 mg/dl or above.

You may note that my figures may not tally with the figures you may see in the lab near you or from where you must have got your recent such analysis of blood work. sad to state but these are the numbers we are supposed to look at when confirming  condition or disease of life style or overall health statistics that may need assistance to correct.

Signs and symptoms vary for Congenital (in-born) metabolic diseases (varying with age too) and these can present in newborns, infants, children, or adults. The onset and severity may be influenced by changes in dietary intake, fasting, dehydration, intercurrent illness, medications, strenuous activity, childbirth, trauma, or surgery.

A metabolic syndrome is defined as the co-occurrence of metabolic risk factors for both type 2 diabetes and cardiovascular disease (CVD) (abdominal obesity, hyperglycemia, dyslipidemia, and hypertension). There are several definitions for the metabolic syndrome. Some definitions you may want to know are :

Parameters NCEP ATP3 2005* IDF 2006 EGIR 1999 WHO 1999 AACE 2003
Required Waist ≥94 cm (men) or ≥80 cm (women)¶ Insulin resistance or fasting hyperinsulinemia in top 25 percent Insulin resistance in top 25 percentΔ; glucose ≥6.1 mmol/L (110 mg/dL); 2-hour glucose ≥7.8 mmol/L (140 mg/dL) High risk of insulin resistance◊ or BMI ≥25 kg/m2 or waist ≥102 cm (men) or ≥88 cm (women)
Number of abnormalities ≥3 of: And ≥2 of: And ≥2 of: And ≥2 of: And ≥2 of:
Glucose ≥5.6 mmol/L (100 mg/dL) or drug treatment for elevated blood glucose ≥5.6 mmol/L (100 mg/dL) or diagnosed diabetes 6.1-6.9 mmol/ (110-125 mg/dL) ≥6.1 mmol/L (110 mg/dL); ≥2-hour glucose 7.8 mmol/L (140 mg/dL)
HDL cholesterol <1.0 mmol/L (40 mg/dL) (men); <1.3 mmol/L (50 mg/dL) (women) or drug treatment for low HDL-C§ <1.0 mmol/L (40 mg/dL) (men); <1.3 mmol/L (50 mg/dL) (women) or drug treatment for low HDL-C <1.0 mmol/L (40 mg/dL) <0.9 mmol/L (35 mg/dL) (men); <1.0 mmol/L (40 mg/dL) (women) <1.0 mmol/L (40 mg/dL) (men); <1.3 mmol/L (50 mg/dL) (women)
Triglycerides ≥1.7 mmol/L (150 mg/dL) or drug treatment for elevated triglycerides§ ≥1.7 mmol/L (150 mg/dL) or drug treatment for high triglycerides or ≥2.0 mmol/L (180 mg/dL) or drug treatment for dyslipidemia or ≥1.7 mmol/L (150 mg/dL) ≥1.7 mmol/L (150 mg/dL)
Obesity Waist ≥102 cm (men) or ≥88 cm (women)¥ Waist ≥94 cm (men) or ≥80 cm (women) Waist/hip ratio >0.9 (men) or >0.85 (women) or BMI ≥30 kg/m2
Hypertension ≥130/85 mmHg or drug treatment for hypertension ≥130/85 mmHg or drug treatment for hypertension ≥140/90 mmHg or drug treatment for hypertension ≥140/90 mmHg ≥130/85 mmHg

These complex table ingredients are complicated and all may not be absolute with the findings given herein. you must refer to your physician or doctor to understand more and not just start feeling sick or using self medication or even get depressed even if you have values or vents that fall within our great table above.

Simple reason for the  above discourse is that lifestyle modifications can help cover the worst and unveil the best in you exercise, food, lowering stress, eating good, abstaining from vices and toxics.

Sundrome as we cal it metabolic Syndrome is a condition not a disease,and also when you try and treat it you treat a symptom like blood pressure, diabetes etc. When you control or take charge you simply manage all parameters with diet exercise and lifestyle, which makes you wise and health. In coming posts we shall visit more in metabolism and see if e can learn and control a few things, at least what we can.


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