MHRA YELLOW CARD REPORTING SUMMARY UP TO 23rd NOVEMBER 2022 (Data published 1st Dec 2022)

Adult & Child – Primary, Third Dose & Boosters (mono/bivalent)

People in UK who have received one or more vaccine = 53,813,491

(Up to 11th Sept 2022)

Yellow Card Adverse Event Reports – 177,925 (Pfizer) + 246,866 (AZ) + 47,045 (Moderna) + 52 (Novavax = N) + 2130 (Unknown) = 474,018 people impacted incl. bivalent vaccines (increase of 3995 in 4 weeks)

Overall 1-in-114 people injected experiences a Yellow Card Adverse Event, which may be less than 10% of actual figures according to MHRA.

TOTAL DOSES administered – 94.4million (Pfizer) + 49.16m (AZ) + 25.3m (Moderna) = 168,859,700 doses incl. all booster programmes

All boosters = 64,259,700

• Pfizer – 32.5m (mono) & 9.7m (bivalent)

• Astrazeneca – 59,700

• Moderna – 13.1m (mono) & 8.9m (bivalent)

Adverse event report figures below INCLUDE both mono- and bivalent COVID-19 mRNA vaccines.

Booster Yellow Card Reports – 35,028 (Pfizer) + 655 (AZ) + 21,956 (Moderna) + 280 (Unknown) = 57,919

Reactions – 511,776 (Pfizer) + 874,912 (AZ) + 151,628 (Moderna) + 106 (Novavax = N) + 6508 (Unknown) = 1,544,930

Fatal – 857 (Pfizer) + 1334 (AZ) + 111 (Moderna) + 60 (Unknown) = 2362

Blood Disorders – 17,677 (Pfizer) + 7938 (AZ) + 2862 (Moderna) + 75 (Unknown) = 28,552

Anaphylaxis – 687 (Pfizer) + 888 (AZ) + 102 (Moderna) + 2 (N) + 3 (Unknown) = 1682

Acute Cardiac – 14,375 (Pfizer) + 11,813 (AZ) + 4177 (Moderna) + 5 (N) + 161 (Unknown) = 30,531

Eye Disorders – 8461 (Pfizer) + 15,107 (AZ) + 1939 (Moderna) + 105 (Unknown) = 25,612

Blindness – 180 (Pfizer) + 330 (AZ) + 46 (Moderna) + 5 (Unknown) = 561

Deafness – 331 (Pfizer) + 447 (AZ) + 70 (Moderna) + 6 (Unknown) = 854

Infections – 13,600 (Pfizer) + 20,951 (AZ) + 3160 (Moderna) + 5 (N) + 263 (Unknown) = 37,979

Herpes – 2341 (Pfizer) + 2725 (AZ) + 363 (Moderna) + 2 (N) + 30 (Unknown) = 5461

Spontaneous Abortions – 505 + 19 stillbirths/foetal deaths (Pfizer) + 240 + 6 stillbirths/foetal deaths (AZ) + 74 + 1 stillbirth (Moderna) +11 (Unknown) = 830 miscarriages

Gastrointestinal Disorders – 44,248 (Pfizer) + 81,396 (AZ) + 13,828 (Moderna) + 6 (N) + 506 (Unknown) = 139,984

Strokes and CNS haemorrhages – 878 (Pfizer) + 2429 (AZ) + 108 (Moderna) + 1 (N) + 27 (Unknown) = 3443

Nervous System Disorders – 84,728 (Pfizer) + 184,225 (AZ) + 24,827 (Moderna) + 16 (N) + 1088 (Unknown) = 294,884

Seizures – 1201 (Pfizer) + 2113 (AZ) + 340 (Moderna) + 34 (Unknown) = 3688

Paralysis – 553 (Pfizer) + 916 (AZ) + 148 (Moderna) + 15 (Unknown) = 1632

Vertigo & Tinnitus – 4426 (Pfizer) + 6935 (AZ) + 925 (Moderna) + 56 (Unknown) = 12,342

Respiratory Disorders – 23,064 (Pfizer) + 30,230 (AZ) + 5592 (Moderna) + 3 (N) + 279 (Unknown) = 59,168

Epistaxis (nosebleeds) – 1148 (Pfizer) + 2307 (AZ) + 240 (Moderna) + 12 (Unknown) = 3707

Psychiatric Disorders – 10,798 (Pfizer) + 18,699 (AZ) + 3025 (Moderna) + 1 (N) + 158 (Unknown) = 32,681

Skin Disorders – 35,879 (Pfizer) + 53,819 (AZ) + 15,036 (Moderna) + 7 (N) + 464 (Unknown) = 105,205

Reproductive/Breast Disorders – 31,789 (Pfizer) + 20,983 (AZ) + 5438 (Moderna) + 1 (N) + 271 (Unknown) = 58,482

Bell’s Palsy – 677 (Pfizer) + 646 (AZ) + 127 (Moderna) + 1 (N) + 3 (Unknown) = 1454

CHILDREN & YOUNG PEOPLE SPECIAL REPORT

Suspected side effects reported in individuals under 18yrs old

Pfizer – 4,200,000 children (1st doses) + 2,900,000 (2nd doses) + 400,000(mono)/52,500(bivalent) boosters resulting in 4205 Yellow Cards

AZ – 11,400 children (1st doses) + 8.500 (2nd doses) + ‘extremely limited boosters’ resulting in 267 Yellow Cards (reporting rate 1-in-43)

Moderna – 2100 children (1st doses) + 2000 (2nd doses) + 32,400(mono)/1000(bivalent) boosters resulting in 39 Yellow cards

Brand Unspecified – 37 Yellow Cards

Total = 4,213,700 children injected (under 18s)

Total doses (1st, 2nd & boosters) = 7,609,900

Total Yellow Cards Under 18s = 4548

For full reports including 387 pages of specific reaction listings https://www.gov.uk/government/publications/coronavirus-covid-19-vaccine-adverse-reactions

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