The ‘Graying’ of T Cells – Immune fitness is twofold: attacking illness-causing cells like bacteria, viruses and cancer and “remembering” past invaders

The elderly suffer more serious complications from infections and benefit less from vaccines.

In a healthy person, T cells circulate in the blood and quietly scan the body for threats using proteins on the cell’s surface. If a T cell encounters another cell it deems dangerous, the T cell undergoes activation, a molecular cascade in which it switches from surveillance mode to attack mode. The activated cells then rapidly replicate to build an army and destroy the enemy.

Source: The ‘Graying’ of T Cells | Harvard Medical School

How are the diseases like fever, cough, and cold etc. classified in contrast to diseases like diabetes, hypertension, and asthma etc.?

Fever

In almost every Out patient department or a clinic often a febrile illness (fever) without an initially obvious etiology (sometimes called fever without localizing signs) as fever of unknown origin (FUO).

GUT- What is really means and why is it gaining significance off late?Our gut is home to approximately 100,000,000,000,000 (100 trillion) microorganisms.

GUTGUT in a layman language may mean NERVE (not the nerves but nerve to perform bold acts), with a slight drift to the medical world or anatomy it may mean Stomach, belly, Abdomen and in literal medicine term it may mean, “gastrointestinal tract”.

The gut is the largest mucosal organ of the body and as such is at the forefront of the body’s immune (ability to fight foreign invasion) homeostasis (also, in regulation of temperature and the balance between acidity and alkalinity (pH). Read through for its importance and its necessity for good health and its role in diabetes, arthritis and other common disorders on the rise!

The creation of genetically modified and entirely synthetic organisms continues to generate excitement as well as worry.

HMS logo news 26th Jan 2015

No Escape

Biological safety lock for genetically modified organisms

By STEPHANIE DUTCHEN
January 21, 2015

Scientists have genetically recoded a strain of <I>E. coli</i> to depend on a synthetic amino acid so the bacteria can’t survive outside the lab. Image: Jennifer HinkleScientists have genetically recoded a strain of E. coli to depend on a synthetic amino acid so the bacteria can’t survive outside the lab. Image: Jennifer Hinkle

The creation of genetically modified and entirely synthetic organisms continues to generate excitement as well as worry.

Such organisms are already churning out insulin and other drug ingredients, helping produce biofuels, teaching scientists about human disease and improving fishing and agriculture. While the risks can be exaggerated to frightening effect, modified organisms do have the potential to upset natural ecosystems if they were to escape.

Predicting Sepsis through blood markers gains ground!!

HMS logoPredicting Sepsis

Altered white-blood-cell motion in burn patients may warn of infection

By SUE McGREEVEY
December 9, 2014HMS researchers  Massachusetts General Hospital have invented a device whose microscopic channels measure abnormal movement patterns of white blood cells called neutrophils, which may predict the development of sepsis in patients with serious burns. Image: BioMEMS Resource Center, Mass General

A team of Harvard Medical School investigators at Massachusetts General Hospital has identified what may be a biomarker predicting the development of sepsis, a dangerous systemic infection in patients with serious burns.

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