Harvard Medical Leading the way through Genetics

It is known that type 2 diabetes can be broadly grouped into cases driven either by the inability of pancreatic beta cells to make enough insulin, known as insulin deficiency, or by the inability of liver, muscle tissues to use insulin, known as insulin resistance.

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Should I be worried if a doctor asks for a bone marrow biopsy?

BMBThe indications, contraindications, technique, and complications of bone marrow aspiration and biopsy are to be carefully known by both the patents and the clinicians.

“Short answer is, you are normal”

BP 2Blood Pressure, a Reading With a Habit of Straying. It turns out that blood pressure can jump around a lot — as much as 40 points in one day in my case — which raises the question of which reading to trust.

Diabetes Prevention Recommendations- Risk, Fasting Glucose, Intervention, levels of glucose, physical activity, prevention

prevention The Community Prevention Services Task Force recommends that healthcare systems and communities provide counseling and longitudinal support to individuals who are at increased risk for type 2 diabetes. some tips and full text can be found here. 

GASTROINTESTINAL CANCER 12-gene recurrence score for resected rectal cancer (January 2015)

Among patients with T3N0 (stage II) colon cancer, gene expression tests such as the 12-gene recurrence score assay are used to refine prognostic stratification and aid in decision making about adjuvant chemotherapy.

The utility of gene scores for prognostication in rectal cancer patients was evaluated in a clinical trial ( Validation of the 12-gene colon cancer recurrence score as a predictor of recurrence risk in stage II and III rectal cancer patients, published by Reimers MS, Kuppen PJ, Lee M, Lopatin M, Tezcan H, Putter H, Clark-Langone K, Liefers GJ, Shak S, van de Velde CJ).

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