Genetic factors offers great promise for the development of novel targeted therapeutics to treat the disease and reduce the risk of fracture.

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Family environment — shared living space and common eating habits — can make a major contribution to a person’s risk of disease like depression.

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Harvard Medical Leading the way through Genetics

It is known that type 2 diabetes can be broadly grouped into cases driven either by the inability of pancreatic beta cells to make enough insulin, known as insulin deficiency, or by the inability of liver, muscle tissues to use insulin, known as insulin resistance.

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GASTROINTESTINAL CANCER 12-gene recurrence score for resected rectal cancer (January 2015)

Among patients with T3N0 (stage II) colon cancer, gene expression tests such as the 12-gene recurrence score assay are used to refine prognostic stratification and aid in decision making about adjuvant chemotherapy.

The utility of gene scores for prognostication in rectal cancer patients was evaluated in a clinical trial ( Validation of the 12-gene colon cancer recurrence score as a predictor of recurrence risk in stage II and III rectal cancer patients, published by Reimers MS, Kuppen PJ, Lee M, Lopatin M, Tezcan H, Putter H, Clark-Langone K, Liefers GJ, Shak S, van de Velde CJ).

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